8 Isekai Anime with A Non-Human Main Character

A growing trend in recent years has been isekai anime, set in an alternate universe. These narratives frequently include a human protagonist who travels to a fantastical universe, but non-human protagonists are also common in isekai anime. In addition to offering a distinct viewpoint, these non-human protagonists frequently possess exceptional skills that set them apart. These are the 8 Isekai Anime where the main character is not human.

Must Watched 8 Isekai Anime with A Non-Human Main Character are as follows:-

1. That Time I Got Reincarnated as a Slime

That Time I Got Reincarnated as a Slime

After being reborn as a slime in a magical universe, Satoru acquires special powers and decides to create a restful neighborhood. He makes allies, makes friends with a variety of animals, and gains the respect of both humans and monsters because to his strong abilities and good nature. Rimuru, the slime, loves growth and diplomacy as he navigates political conflict, looks out for his new family, and strives to make the world a peaceful place for everyone.

2. Overlord


As his skeletal avatar, Momonga, an exceptional player in “Overlord,” is imprisoned in a virtual gaming environment. He takes on the role of Ainz Ooal Gown, the formidable king, maintaining the stronghold of his gang. With a strong desire to investigate this new reality, he gains the loyalty of NPCs, increases his power, and looks for answers regarding this strange universe. On a quest for domination, Ainz must balance dark powers and strategic choices. He faces obstacles as he discovers the truths about his changed life.

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3. The Rising of the Shield Hero

The Rising of the Shield Hero

In “The Rising of the Shield Hero”, Naofumi Iwatani, who is called to a parallel dimension in the form of the Shield Hero, must confront betrayal after being wrongly accused of a crime. He withdraws and becomes unhappy, depending only on his defensive abilities. He overcomes prejudice and mistrust while fighting waves of tragedy to preserve the planet with the help of unexpected allies like the demi-human slave Raphtalia. Naofumi’s resolve to defend himself endures hardship, transforming him from a mistrustful introvert into a kind hero who seeks justice and forgiveness in a complex and challenging world.

4. Kemono Michi: Rise Up

Kemono Michi: Rise Up

“Kemono Michi: Rise Up” centers on Genzou Shibata, a professional wrestler who gets thrust into a fantastical world and has to fight with demonic creatures. He starts a pet store instead of hurting animals, though. With the help of a group of unusual creatures, including a wolf-girl, and his beastman skills, Genzou overcomes obstacles by striking a balance between his love of animals and society’s expectations. He fights opponents and promotes animal rights through amusing encounters and strange alliances. Genzou’s nontraditional career path demonstrates his constant commitment to safeguarding and tending to animals, fusing action, comedy, and compassion in a world inhabited by legendary creatures and crazy situations.

5. Re:Zero – Starting Life in Another World

Re:Zero - Starting Life in Another World

“Re:Zero – Starting Life in Another World” centers on Subaru Natsuki, who, upon passing away, finds herself able to travel back in time to a certain moment after being carried to a magical universe. Subaru faces powerful opponents and undergoes multiple tragedies in his efforts to save those he loves and understand the secrets of his strength. Making friends with Emilia and other people, he negotiates political plots and conflicts, frequently having to make sacrifices and face despair. In this intricate and tragic story, Subaru builds a path toward forgiveness and discovers the mysteries underlying his amazing gift through resilience and personal growth. Subaru learns to rely on allies, adjust techniques, and confront his inner demons.

6. Saga of Tanya the Evil

 Saga of Tanya the Evil

The main character of “Saga of Tanya the Evil” is Tanya Degurechaff, an immoral salaryman who was reborn as a little child in a parallel universe damaged by conflict. Tanya advances through the ranks with great magical abilities and a military mentality, trying to ensure a safe life while avoiding the horrors of war. She manipulates circumstances to secure her life when faced with moral quandaries, gaining the moniker “Devil of the Rhine.” In a world where strength is everything, Tanya’s strategic intelligence, sly moves against adversaries, and philosophical reflections create a captivating story that explores the nature of warfare, ambition, and its effects against the backdrop of a war.

7. Made in Abyss

Made in Abyss

“Made in Abyss” covers the adventures of a humanoid robot named Reg and a young girl named Riko as they investigate the mysterious Abyss, a huge abyss full of wonderful creatures and relics. They go into its terrible depths in search of Riko’s missing mother, coming across dangerous obstacles and a variety of sceneries.

The pair faces ethical issues and emotional challenges as they make their way through the Abyss’s layers and reveal its secrets. Riko and Reg’s relationship grows stronger in the face of dangerous encounters and stunning landscape, pulling them forward despite the Abyss’s harshness. Explore the cost of exploration and the attraction of the unknown in this series that features breathtaking animation and a mix of adventure and sadness.

8. Drifters


The plot of “Drifters” centers on historical fighters, such as Shimazu Toyohisa, who are sent to a magical universe to fight the Ends, who are represented by villains from the past. Accompanied by notable personalities such as Oda Nobunaga and Hannibal Barca, they establish the Drifters, a group that opposes the violent Ends. They form relationships with the locals and explore their newfound talents as they plot to stop global dominance in the middle of conflicts. “Drifters” is a story about epic battles, philosophies, and the conflict of famous warriors that confront ideas of good and evil as well as the chase of power. It does this by fusing fantasy, historical personalities, and action.


These series, which have protagonists that are non-humans and go into exciting fantastical realms, each offer their own version of the isekai genre.
These are only a few of isekai anime series featuring non-human protagonists. With them, the isekai genre gains a fresh viewpoint. Have you watched any of these anime? Let us know in the comments.

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